0031-9155/58/10/3191
Abstract
A multi-slot coaxial microwave antenna for liver tumor ablation Mengke 1Ge,4, Hejun Jiang 1, Xiaoyan Huang 1, Yufu Zhou, Debo Zhi 1, Gang Zhao 1,2, Yuping Chen, Lulu Wang 3,5 and Bensheng Qiu 1 1 Centers for Biomedical Engineering, Department of Electronic Science and Technology, University of Science and Technology of China.
Microwave ablation is a technique used in treating hepatocellular carcinoma, especially in cases where surgical removal is impossible. In the present study we are investigating the effects of design characteristics of a coaxial slot antenna (single- versus double-slot, slot-to-tip distance and slot size) on the ablation zone characteristics (dimensions and shape). The specific absorption rate field and the temperature rises are calculated for a variety of application times and powers. A plateau in the ablation zone dimensions in healthy and cirrhotic liver models is predicted, but not in malignant ones. It is found that the value of the perfusion rate (which is different for each clinical case) is of crucial importance in order to correctly estimate the ablation zone. An underestimation of dimensions is expected, if higher perfusion rates are used (i.e., values for healthy tissue rather than malignant). In contrast, an exact determination of the values of relative permittivity and conductivity is less significant for predicting the ablation zone.
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General scientific summary Microwave ablation (MWA) is a novel, minimally invasive, thermal-based technique used in treating hepatocellular carcinoma. In this study we present clinically relevant numerical models, aimed to quantify the characteristics (dimensions and shape) of the ablation zones. Such information can aid in patient-specific pre-treatment planning. Coaxial antennas of different designs (single- vs double-slot, various slot-to-tip distances and slot sizes) were modelled and their performance was compared. Double-slot antennas in the range of about 10 mm were found efficient. Regarding modelling the tissue, we showed that the value of perfusion rate (which is different for each clinical case) determines the behaviour of the ablation zone. Its correct evaluation is of crucial importance to estimate the extent of heating. As a step to close the gap between experimental and theoretical studies, we showed that an underestimation of dimensions is expected when higher perfusion rates (as such of healthy rather than malignant liver) are considered.
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Slot Antenna For Microwave Ablation Surgery
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